WHO: Ebola disease - Diagnosis
April 24, 2025
Source: WHO
Photo / Image Source: Unsplash,
Diagnosis
It can be difficult to clinically distinguish Ebola disease from other infectious diseases such as malaria, typhoid fever, shigellosis, meningitis and other viral haemorrhagic fevers because symptoms at early stage of the disease are similar.
Confirmation that the person has an Orthoebolavirus infection is made using the following diagnostic methods:
reverse transcriptase polymerase chain reaction (RT-PCR) assay
antibody-capture enzyme-linked immunosorbent assay (ELISA)
antigen-capture detection tests
virus isolation by cell culture.
Samples collected from patients are an extreme biohazard risk; laboratory testing on non-inactivated samples should be conducted under maximum biological containment conditions. All non-inactivated biological specimens should be packaged using the triple packaging system when transported nationally and internationally See Diagnostic testing for Ebola and Marburg diseases.
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