Intellectual Property & Your Health Series - Genomics applications
- Shidonna Raven
- Jun 2
- 1 min read
Source: Britannica
Photo / Image Source: Unsplash,
Before you go to the Doctor!
Genomics applications
Analysis of genes at the functional level is one of the main uses of genomics, an area known generally as functional genomics. Determining the function of individual genes can be done in several ways. Classical, or forward, genetic methodology starts with a randomly obtained mutant of interesting phenotype and uses this to find the normal gene sequence and its function. Reverse genetics starts with the normal gene sequence (as obtained by genomics), induces a targeted mutation into the gene, then, by observing how the mutation changes phenotype, deduces the normal function of the gene. The two approaches, forward and reverse, are complementary. Often a gene identified by forward genetics has been mapped to one specific chromosomal region, and the full genomic sequence reveals a gene in this position with an already annotated function. (For more information about genetic studies, see genetics: Methods in genetics.)
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